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KMID : 0853020190220020042
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Journal of Korean Burn Society
2019 Volume.22 No. 2 p.42 ~ p.48
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Feasibility of Cultured Allogenic Keratinocyte Treatment for Third Degree Burns
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Choi Jang-Youn
Cho Jin-Tae
Choi Jong-Yun
Seo Bo-Mie
Jung Sung-No
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Abstract
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Allogenic keratinocyte application is widely used for treatment of second degree burns. However, there is no significant body of report on application of allogenic keratinocyte to third degree burns. A geriatric patient visited our burn center showing second to third-degree burn on dorsum of her left hand. Considering the surface area and wound depth, surgery was indicated but her medical condition and age made the surgery high risk for a long operation. Therefore, chemical escharolysis, serial bedside debridement, and cultured allogenic keratinocyte (Kaloderm®, Tegoscience, Seoul, Korea) application was done. The wound was completely epithelialized after four rounds of Kaloderm® application. For third-degree burns where definitive surgical reconstruction is precluded due to medical comorbidity of the patient, we investigated the possibility of allogenic keratinocyte treatment which may allow to avoid high-risk anesthesia and surgery.
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KEYWORD
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Burn, Keratinocyte, Wound healing, Cell-and-tissue-based therapy
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